PRP可用於異位性皮膚炎和其他類型的濕疹
PRP可用於異位性皮膚炎和其他類型的濕疹
從一例異位性皮膚炎患者注射PRP獲得的療效可看出，使用 PRP 成功控制皮膚症狀，且達到年輕化的目的。
PRP科技新知- PRP可用於異位性皮膚炎和其他類型的濕疹
這是一篇個案報告
前言:
異位性皮膚炎是一種慢性皮膚發炎疾病，最常見於兒童時期，但也影響許多成年人。大多數異位性皮膚炎患者使用保濕劑和外用類固醇進行治療。然而，這些治療並不總是能夠良好控制疾病。富含血小板血漿 (PRP) 用於治療許多皮膚病。PRP是經由血小板釋放各種物質（例如生長因子）發揮作用，從而誘導傷口癒合的一系列反應，包括抗發炎和組織再生，從而促進皮膚健康。這篇文章報導了一例異位性皮膚炎患者，使用 PRP 成功控制皮膚症狀。
個案報告:
一名 44 歲的女性於 2016 年 5 月就診，有長期反覆面部濕疹病史。患者使用類固醇乳膏六個月後，效果不佳，並且也詢問眼眶下黑眼圈和皺紋的治療方法。在討論治療方式後，決定進行 PRP 注射。 使用 4-cc 富含血小板的纖維蛋白基質試劑盒 (Selphyl, Aesthetic Factors, Inc) 進行了兩次 PRP 針劑注射治療，每次間隔 6 週。 除了在眼睛下方施用外，PRP 也使用在鼻唇溝中以達到年輕化的目的。
圖：面部濕疹對 PRP 針劑注射治療的效果。
結論:
根據這篇文章和其他研究的結果，PRP 可用於治療異位性皮膚炎和其他類型的濕疹。這位病人追蹤觀察兩年，症狀緩解是前所未有的。
原文摘要：
Atopic dermatitis (AD) is a chronic inflammatory skin condition that most often presents in childhood but also affects many adults. Most patients with AD are treated with moisturizers and topical corticosteroids. However, these treatments do not always allow for an adequate control of the disease. Platelet-rich plasma (PRP) is used in treating many dermatologic conditions. It works by releasing bioagents, such as growth factors, from platelets, which induce a wound-healing cascade involving inflammation and tissue regeneration that promotes skin health. Here, we report a case of AD in which the patient successfully achieved an extended control of skin symptoms with PRP therapy.
A 44-year-old woman presented in May 2016 with a long-standing history of recurrent facial eczema. Six months later, the patient returned for a refill of the hydrocortisone cream and inquired about treatments for infraorbital dark circles and wrinkles. After discussing the treatment options, we decided to proceed with PRP injections, and informed consent was obtained. Two PRP therapy sessions were performed, spaced 6 weeks apart, using a 4-cc platelet-rich fibrin matrix kit (Selphyl, Aesthetic Factors, Inc). In addition to administration beneath the eyes, PRP was also administered into nasolabial folds for rejuvenation purposes.
Fig 1: Response of facial eczema to PRP treatment.
Based on our results and those of other studies, there is an indication for the potential use of PRP in the management of AD and other types of eczema. Two years of symptom relief is unprecedented. A randomized clinical trial with a greater number of participants is warranted to rigorously evaluate the seemingly positive effects of PRP in treating skin eczema, including AD. Further research may also shed more light on the pathophysiology of AD as well as the biochemical pathways through which PRP can exert its therapeutic effects.
文章出處:
Saba Vafaei-Nodeh, BSc, and Shadan Kabiri-Abyaneh, MD, CCFP. Long-term control of atopic dermatitis with platelet-rich plasma. JAAD Case Rep. 2020 Nov 5;7:54-56.
這是一篇個案報告
前言:
異位性皮膚炎是一種慢性皮膚發炎疾病，最常見於兒童時期，但也影響許多成年人。大多數異位性皮膚炎患者使用保濕劑和外用類固醇進行治療。然而，這些治療並不總是能夠良好控制疾病。富含血小板血漿 (PRP) 用於治療許多皮膚病。PRP是經由血小板釋放各種物質（例如生長因子）發揮作用，從而誘導傷口癒合的一系列反應，包括抗發炎和組織再生，從而促進皮膚健康。這篇文章報導了一例異位性皮膚炎患者，使用 PRP 成功控制皮膚症狀。
個案報告:
一名 44 歲的女性於 2016 年 5 月就診，有長期反覆面部濕疹病史。患者使用類固醇乳膏六個月後，效果不佳，並且也詢問眼眶下黑眼圈和皺紋的治療方法。在討論治療方式後，決定進行 PRP 注射。 使用 4-cc 富含血小板的纖維蛋白基質試劑盒 (Selphyl, Aesthetic Factors, Inc) 進行了兩次 PRP 針劑注射治療，每次間隔 6 週。 除了在眼睛下方施用外，PRP 也使用在鼻唇溝中以達到年輕化的目的。
圖：面部濕疹對 PRP 針劑注射治療的效果。
結論:
根據這篇文章和其他研究的結果，PRP 可用於治療異位性皮膚炎和其他類型的濕疹。這位病人追蹤觀察兩年，症狀緩解是前所未有的。
原文摘要：
Atopic dermatitis (AD) is a chronic inflammatory skin condition that most often presents in childhood but also affects many adults. Most patients with AD are treated with moisturizers and topical corticosteroids. However, these treatments do not always allow for an adequate control of the disease. Platelet-rich plasma (PRP) is used in treating many dermatologic conditions. It works by releasing bioagents, such as growth factors, from platelets, which induce a wound-healing cascade involving inflammation and tissue regeneration that promotes skin health. Here, we report a case of AD in which the patient successfully achieved an extended control of skin symptoms with PRP therapy.
A 44-year-old woman presented in May 2016 with a long-standing history of recurrent facial eczema. Six months later, the patient returned for a refill of the hydrocortisone cream and inquired about treatments for infraorbital dark circles and wrinkles. After discussing the treatment options, we decided to proceed with PRP injections, and informed consent was obtained. Two PRP therapy sessions were performed, spaced 6 weeks apart, using a 4-cc platelet-rich fibrin matrix kit (Selphyl, Aesthetic Factors, Inc). In addition to administration beneath the eyes, PRP was also administered into nasolabial folds for rejuvenation purposes.
Fig 1: Response of facial eczema to PRP treatment.
Based on our results and those of other studies, there is an indication for the potential use of PRP in the management of AD and other types of eczema. Two years of symptom relief is unprecedented. A randomized clinical trial with a greater number of participants is warranted to rigorously evaluate the seemingly positive effects of PRP in treating skin eczema, including AD. Further research may also shed more light on the pathophysiology of AD as well as the biochemical pathways through which PRP can exert its therapeutic effects.
文章出處:
Saba Vafaei-Nodeh, BSc, and Shadan Kabiri-Abyaneh, MD, CCFP. Long-term control of atopic dermatitis with platelet-rich plasma. JAAD Case Rep. 2020 Nov 5;7:54-56.